About Heart Failure

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What is heart failure?

Heart failure happens when your heart is weak and cannot pump enough blood to your lungs and the rest of your body.

Symptoms of heart failure

Symptoms of heart failure

A fast heartbeat; shortness of breath; ongoing coughing or wheezing; feeling dizzy, weak, or tired; or swelling of the feet or legs. These are not the only symptoms of heart failure.

Heart failure treatment

Looking for a conversation starter to help you talk to your doctor about treatment? This handy guide includes some questions to bring to your next appointment, so you and your doctor can see if VERQUVO is right for you.

Download Doctor Discussion Guide

Hospitalization

About 1 million people in the United States are hospitalized every year with heart failure.

A heart failure hospitalization may increase your chances of going back to the hospital. About 56% of patients hospitalized (or who receive IV medicine) due to increased heart failure symptoms return to the hospital within 30 days.*

* From a study of heart failure patients in the National PINNACLE Registry, where 1,851 patients with ejection fraction (amount of blood pumped with each heartbeat) less than or equal to 45% had increased symptoms of heart failure that required hospitalization or IV medicine.

VERQUVO is the first and only FDA-approved medicine studied specifically in patients who had a recent heart failure hospitalization or received IV medicine for their heart failure.‡

  • Over 5,000 people with heart failure participated

‡Patients had been hospitalized within the previous 6 months or had received IV medicine for heart failure within the previous 3 months

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Discover VERQUVO

VERQUVO is a prescription medicine used in adults who are having symptoms of their chronic (long-lasting) heart failure, who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent to reduce the risk of dying and to reduce the need to be hospitalized.

Discover VERQUVO

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What is VERQUVO?

VERQUVO is a prescription medicine used in adults who are having symptoms of their chronic (long-lasting) heart failure, who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent to reduce the risk of dying and to reduce the need to be hospitalized.

IMPORTANT SAFETY INFORMATION

VERQUVO may cause birth defects if taken during pregnancy.

  • Females must not be pregnant when they start taking VERQUVO.
  • For females who are able to get pregnant:
    • Your healthcare provider will do a pregnancy test to make sure that you are not pregnant before you start taking VERQUVO.
    • You must use effective forms of birth control during treatment and for 1 month after you stop treatment with VERQUVO. Talk to your healthcare provider about forms of birth control that you may use to prevent pregnancy during treatment.
    • Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with VERQUVO.
    • There is a Pregnancy Surveillance Program that monitors pregnancy outcomes in women exposed to VERQUVO during pregnancy. Patients should report any exposure to VERQUVO during pregnancy by calling 1-877-888-4231 or at https://pregnancyreporting.verquvo-us.com.

Do not take VERQUVO if you:

  • are taking another medicine called a soluble guanylate cyclase stimulator (sGC). Ask your healthcare provider if you are not sure if you are taking an sGC medicine.
  • are pregnant.

Before taking VERQUVO, tell your healthcare provider about all your medical conditions, including if you:

  • are breastfeeding or plan to breastfeed. It is not known if VERQUVO passes into your breast milk. Do not breastfeed if you take VERQUVO. Talk with your healthcare provider about the best way to feed your baby if you take VERQUVO.

Tell your healthcare provider about all the medicines you take. Certain other medicines may affect how VERQUVO works.

The most common side effects of VERQUVO include:

  • low blood pressure
  • low red blood cells (anemia)

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 

Please read the accompanying Medication Guide for VERQUVO, including the information about birth defects if taken during pregnancy, and discuss it with your doctor. The physician Prescribing Information also is available.

What is VERQUVO® (vericiguat)?

VERQUVO is a prescription medicine used in adults who are having symptoms of their chronic (long-lasting) heart failure, who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent to reduce the risk of dying and to reduce the need to be hospitalized.

VERQUVO is a prescription medicine used in adults who are having symptoms

VERQUVO is a prescription medicine used in adults who are having symptoms of their chronic (long-lasting) heart failure, who have had a recent hospitalization or the need to receive intravenous (IV) medicines and have an ejection fraction (amount of blood pumped with each heartbeat) of less than 45 percent to reduce the risk of dying and to reduce the need to be hospitalized.

IMPORTANT SAFETY INFORMATION for VERQUVO® (vericiguat)

VERQUVO may cause birth defects if taken during pregnancy.

  • Females must not be pregnant when they start taking VERQUVO.
  • For females who are able to get pregnant:
    • Your healthcare provider will do a pregnancy test to make sure that you are not pregnant before you start taking VERQUVO.
    • You must use effective forms of birth control during treatment and for 1 month after you stop treatment with VERQUVO. Talk to your healthcare provider about forms of birth control that you may use to prevent pregnancy during treatment.
    • Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with VERQUVO.
    • There is a Pregnancy Surveillance Program that monitors pregnancy outcomes in women exposed to VERQUVO during pregnancy. Patients should report any exposure to VERQUVO during pregnancy by calling 1-877-888-4231 or at https://pregnancyreporting.verquvo-us.com.

Do not take VERQUVO if you:

  • are taking another medicine called a soluble guanylate cyclase stimulator (sGC). Ask your healthcare provider if you are not sure if you are taking an sGC medicine.
  • are pregnant.

Before taking VERQUVO, tell your healthcare provider about all your medical conditions, including if you:

  • are breastfeeding or plan to breastfeed. It is not known if VERQUVO passes into your breast milk. Do not breastfeed if you take VERQUVO. Talk with your healthcare provider about the best way to feed your baby if you take VERQUVO.

Tell your healthcare provider about all the medicines you take. Certain other medicines may affect how VERQUVO works.

The most common side effects of VERQUVO include:

  • low blood pressure
  • low red blood cells (anemia)

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 

Please read the accompanying Medication Guide for VERQUVO, including the information about birth defects if taken during pregnancy, and discuss it with your doctor. The physician Prescribing Information also is available.

VERQUVO may cause birth defects if taken during pregnancy.

  • Females must not be pregnant when they start taking VERQUVO.
  • For females who are

VERQUVO may cause birth defects if taken during pregnancy.

  • Females must not be pregnant when they start taking VERQUVO.
  • For females who are able to get pregnant:
    • Your healthcare provider will do a pregnancy test to make sure that you are not pregnant before you start taking VERQUVO.